< iframe width =" 425" height=" 355 "src= "https://www.youtube.com/embed/AlPVFMDCOY0?rel=0" frameborder=" 0" allowfullscreen > Jennifer L. Costello, PharmD, BCPS, BC-ADM, ambulatory treatment medical pharmacist at Saint Barnabas Medical Center, evaluates the pharmacologic mechanisms in the new weight-loss drugs.
Liraglutide, a glucagon-like peptide-1 receptor agonist, helps boost insulin secretion and decrease glucagon release. The drug drastically affects individual satiation, so they consume less, Dr. Costello notes. It likewise causes some gastrointestinal distress, which can make some individuals eat much less.
At the same time, the naltrexone/bupropion combination affects main nerves synapses by boosting or modulating the desire zone– creating individuals to have fewer food cravings.
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